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Evolutionary History and Genome Organization of DUF1220 Protein Domains
DUF1220 protein domains exhibit the most extreme human lineage–specific (HLS) copy number increase of any protein coding region in the human genome and have recently been linked to evolutionary and pathological changes in brain size (e.g., 1q21‐associated microcephaly). These findings lend support t...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Genetics Society of America
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429928/ https://ncbi.nlm.nih.gov/pubmed/22973535 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.112.003061 |
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