Generation of mice lacking DUF1220 protein domains: effects on fecundity and hyperactivity

Sequences encoding DUF1220 protein domains show the most extreme human lineage-specific copy number increase of any coding region in the genome and have been linked to human brain evolution. In addition, DUF1220 copy number (dosage) has been implicated in influencing brain size within the human spec...

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Detalhes bibliográficos
Publicado no:Mamm Genome
Main Authors: Keeney, JG, O’Bleness, MS, Anderson, N, Davis, JM, Arevalo, N, Busquet, N, Chick, W, Rozman, J, Hölter, SM, Garrett, L, Horsch, M, Beckers, J, Wurst, W, Klingenspor, M, Restrepo, D, Hraběde Angelis, M, Sikela, JM
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4305498/
https://ncbi.nlm.nih.gov/pubmed/25308000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-014-9545-8
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