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DUF1220 Domains, Cognitive Disease, and Human Brain Evolution
We have established that human genome sequences encoding a novel protein domain, DUF1220, show a dramatically elevated copy number in the human lineage (>200 copies in humans vs. 1 in mouse/rat) and may be important to human evolutionary adaptation. Copy-number variations (CNVs) in the 1q21.1 reg...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2902282/ https://ncbi.nlm.nih.gov/pubmed/19850849 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/sqb.2009.74.025 |
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