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The in Vitro – in Vivo Translation of Lipid Nanoparticles for Hepatocellular siRNA Delivery
A significant challenge in the development of clinically-viable siRNA delivery systems is a lack of in vitro – in vivo translatability: many delivery vehicles that are initially promising in cell culture do not retain efficacy in animals. Despite its importance, little information exists on the pred...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429655/ https://ncbi.nlm.nih.gov/pubmed/22770391 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn301922x |
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