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Oral delivery of siRNA lipid nanoparticles: Fate in the GI tract

Oral delivery, a patient-friendly means of drug delivery, is preferred for local administration of intestinal therapeutics. Lipidoid nanoparticles, which have been previously shown to deliver siRNA to intestinal epithelial cells, have potential to treat intestinal disease. It is unknown, however, wh...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Sci Rep
Main Authors: Ball, Rebecca L., Bajaj, Palak, Whitehead, Kathryn A.
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5794865/
https://ncbi.nlm.nih.gov/pubmed/29391566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-20632-6
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