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Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma
The development of targeted therapies and immunotherapies has markedly advanced the treatment of metastasized melanoma. While treatment with selective BRAF(V600E) inhibitors (like vemurafenib or dabrafenib) leads to high response rates but short response duration, CTLA-4 blocking therapies induce su...
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| Autori principali: | , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2012
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429565/ https://ncbi.nlm.nih.gov/pubmed/22934253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20226 |
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