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Selective BRAF inhibition decreases tumor-resident lymphocyte frequencies in a mouse model of human melanoma
The development of targeted therapies and immunotherapies has markedly advanced the treatment of metastasized melanoma. While treatment with selective BRAF(V600E) inhibitors (like vemurafenib or dabrafenib) leads to high response rates but short response duration, CTLA-4 blocking therapies induce su...
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| 主要な著者: | , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Landes Bioscience
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429565/ https://ncbi.nlm.nih.gov/pubmed/22934253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/onci.20226 |
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