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Defective mitophagy in human Niemann-Pick Type C1 neurons is due to abnormal autophagy activation
Although traditionally regarded as a cellular adaptive process triggered by nutrient deprivation, autophagy in neurons appears to provide an important neuroprotective mechanism. Neurons in the brain are protected from starvation, and neuronal autophagy serves a critical role in the turnover of abnor...
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Landes Bioscience
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3429558/ https://ncbi.nlm.nih.gov/pubmed/22647841 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20668 |
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