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Disruption and therapeutic rescue of autophagy in a human neuronal model of Niemann Pick type C1
An unresolved issue about many neurodegenerative diseases is why neurons are particularly sensitive to defects in ubiquitous cellular processes. One example is Niemann Pick type C1, caused by defects in cholesterol trafficking in all cells, but where neurons are preferentially damaged. Understanding...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3363339/ https://ncbi.nlm.nih.gov/pubmed/22437840 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/dds090 |
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