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Anatomically Defined Neuron-Based Rescue of Neurodegenerative Niemann–Pick Type C Disorder
Niemann–Pick type C disease is a fatal lysosomal storage disorder caused by loss of NPC1 function. The disorder severely affects multiple body systems, particularly the nervous system. To test whether rescue of NPC1 activity in neurons, astrocytes, or other cell types can correct the neurological de...
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| Главные авторы: | , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Society for Neuroscience
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3071647/ https://ncbi.nlm.nih.gov/pubmed/21430138 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5981-10.2011 |
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