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Gadolinium Chloride Rescues Niemann–Pick Type C Liver Damage

Niemann–Pick type C (NPC) disease is a rare neurovisceral cholesterol storage disorder that arises from loss of function mutations in the NPC1 or NPC2 genes. Soon after birth, some patients present with an aggressive hepatosplenomegaly and cholestatic signs. Histopathologically, the liver presents w...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Klein, Andrés D., Oyarzún, Juan Esteban, Cortez, Cristian, Zanlungo, Silvana
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6274821/
https://ncbi.nlm.nih.gov/pubmed/30441844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms19113599
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