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Anatomically Defined Neuron-Based Rescue of Neurodegenerative Niemann–Pick Type C Disorder

Niemann–Pick type C disease is a fatal lysosomal storage disorder caused by loss of NPC1 function. The disorder severely affects multiple body systems, particularly the nervous system. To test whether rescue of NPC1 activity in neurons, astrocytes, or other cell types can correct the neurological de...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Lopez, Manuel E., Klein, Andres D., Dimbil, Ubah J., Scott, Matthew P.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3071647/
https://ncbi.nlm.nih.gov/pubmed/21430138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5981-10.2011
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