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Defective mitophagy in human Niemann-Pick Type C1 neurons is due to abnormal autophagy activation

Although traditionally regarded as a cellular adaptive process triggered by nutrient deprivation, autophagy in neurons appears to provide an important neuroprotective mechanism. Neurons in the brain are protected from starvation, and neuronal autophagy serves a critical role in the turnover of abnor...

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Detalhes bibliográficos
Autor principal: Ordonez, Maria Paulina
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429558/
https://ncbi.nlm.nih.gov/pubmed/22647841
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/auto.20668
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