Toll-Like Receptor (TLR2 and TLR4) Polymorphisms and Chronic Obstructive Pulmonary Disease

Toll-like receptors (TLRs) participate in the defence against bacterial infections that are common in patients with Chronic Obstructive Pulmonary Disease (COPD). We studied all tagging SNPs in TLR2 and TLR4 and their associations with the level and change over time of both FEV(1) and sputum inflamma...

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Autori principali: Budulac, Simona E., Boezen, H. Marike, Hiemstra, Pieter S., Lapperre, Therese S., Vonk, Judith M., Timens, Wim, Postma, Dirkje S.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3429472/
https://ncbi.nlm.nih.gov/pubmed/22952638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043124
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