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Molecular cycloencapsulation augments solubility and improves therapeutic index of brominated noscapine in prostate cancer cells
We have previously shown that a novel microtubule-modulating noscapinoid, EM011 (9-Br-Nos), displays potent anticancer activity by inhibition of cellular proliferation and induction of apoptosis in prostate cancer cells and preclinical mice models. However, physicochemical and cellular barriers encu...
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| 主要な著者: | , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3428378/ https://ncbi.nlm.nih.gov/pubmed/22540277 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300063v |
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