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Enhanced noscapine delivery using uPAR-targeted optical-MR imaging trackable nanoparticles for prostate cancer therapy

The tubulin-binding anticancer activity of noscapine, an orally-available plant-derived anti-tussive alkaloid, has been recently identified. Noscapine inhibits tumor growth in nude mice bearing human xenografts of hematopoietic, breast, lung, ovarian, brain and prostate origin. Despite its non-toxic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Abdalla, Mohamed O., Karna, Prasanthi, Sajja, Hari Krishna, Mao, Hui, Yates, Clayton, Turner, Timothy, Aneja, Ritu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3179860/
https://ncbi.nlm.nih.gov/pubmed/21047537
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2010.10.030
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