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Potent Anti-Inflammatory Activity of Novel Microtubule-Modulating Brominated Noscapine Analogs
Noscapine, a plant-derived, non-toxic, over-the-counter antitussive alkaloid has tubulin-binding properties. Based upon the structural resemblance of noscapine to colchicine, a tubulin-binding anti-inflammatory drug, noscapine and its semi-synthetic brominated analogs were examined for in vitro anti...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2010
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2820095/ https://ncbi.nlm.nih.gov/pubmed/20161797 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0009165 |
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