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Second generation benzofuranone ring substituted noscapine analogs: Synthesis and biological evaluation
Microtubules, composed of α/β tubulin heterodimers, represent a validated target for cancer chemotherapy. Thus, tubulin- and microtubule-binding antimitotic drugs such as taxanes and vincas are widely employed for the chemotherapeutic management of various malignancies. Although quite successful in...
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| Main Authors: | , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3179862/ https://ncbi.nlm.nih.gov/pubmed/21501599 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2011.03.029 |
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