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Induction of Reactive Oxygen Species-mediated Autophagy by a Novel Microtubule-modulating Agent

Autophagy is being increasingly implicated in both cell survival and death. However, the intricate relationships between drug-induced autophagy and apoptosis remain elusive. Here we demonstrate that a tubulin-binding noscapine analog, (R)-9-bromo-5-((S)-4,5-dimethoxy-1,3-dihydroisobenzofuran-1-yl)-4...

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Detalhes bibliográficos
Main Authors: Karna, Prasanthi, Zughaier, Susu, Pannu, Vaishali, Simmons, Robert, Narayan, Satya, Aneja, Ritu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2881797/
https://ncbi.nlm.nih.gov/pubmed/20404319
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.091694
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