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Mechanism of Action of Phenethylisothiocyanate and Other Reactive Oxygen Species-Inducing Anticancer Agents

Reactive oxygen species (ROS)-inducing anticancer agents such as phenethylisothiocyanate (PEITC) activate stress pathways for killing cancer cells. Here we demonstrate that PEITC-induced ROS decreased expression of microRNA 27a (miR-27a)/miR-20a:miR-17-5p and induced miR-regulated ZBTB10/ZBTB4 and Z...

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Detaylı Bibliyografya
Asıl Yazarlar: Jutooru, Indira, Guthrie, Aaron S., Chadalapaka, Gayathri, Pathi, Satya, Kim, KyoungHyun, Burghardt, Robert, Jin, Un-Ho, Safe, Stephen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4054319/
https://ncbi.nlm.nih.gov/pubmed/24732804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01602-13
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