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Aspirin Inhibits Colon Cancer Cell and Tumor Growth and Downregulates Specificity Protein (Sp) Transcription Factors

Acetylsalicylic acid (aspirin) is highly effective for treating colon cancer patients postdiagnosis; however, the mechanisms of action of aspirin in colon cancer are not well defined. Aspirin and its major metabolite sodium salicylate induced apoptosis and decreased colon cancer cell growth and the...

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Detalhes bibliográficos
Main Authors: Pathi, Satya, Jutooru, Indira, Chadalapaka, Gayathri, Nair, Vijayalekshmi, Lee, Syng-Ook, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3482208/
https://ncbi.nlm.nih.gov/pubmed/23110215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0048208
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