Metformin inhibits pancreatic cancer cell and tumor growth and downregulates Sp transcription factors

Metformin is a widely used antidiabetic drug, and epidemiology studies for pancreatic and other cancers indicate that metformin exhibits both chemopreventive and chemotherapeutic activities. Several metformin-induced responses and genes are similar to those observed after knockdown of specificity pr...

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Hlavní autoři: Nair, Vijayalekshmi, Pathi, Satya, Jutooru, Indira, Sreevalsan, Sandeep, Basha, Riyaz, Abdelrahim, Maen, Samudio, Ismael, Safe, Stephen
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2013
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Original Manuscript
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3845888/
https://ncbi.nlm.nih.gov/pubmed/23803693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/carcin/bgt231
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