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DRUGS THAT TARGET SPECIFICITY PROTEINS DOWNREGULATE EPIDERMAL GROWTH FACTOR RECEPTOR IN BLADDER CANCER CELLS
The epidermal growth factor receptor (EGFR) is an important chemotherapeutic target for tyrosine kinase inhibitors and antibodies that block the extracellular domain of EGFR. Betulinic acid (BA) and curcumin inhibited bladder cancer cell growth and downregulated specificity protein (Sp) transcriptio...
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| Autori principali: | , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2010
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2872686/ https://ncbi.nlm.nih.gov/pubmed/20407012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0493 |
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