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DRUGS THAT TARGET SPECIFICITY PROTEINS DOWNREGULATE EPIDERMAL GROWTH FACTOR RECEPTOR IN BLADDER CANCER CELLS

The epidermal growth factor receptor (EGFR) is an important chemotherapeutic target for tyrosine kinase inhibitors and antibodies that block the extracellular domain of EGFR. Betulinic acid (BA) and curcumin inhibited bladder cancer cell growth and downregulated specificity protein (Sp) transcriptio...

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Detalhes bibliográficos
Main Authors: Chadalapaka, Gayathri, Jutooru, Indira, Burghardt, Robert, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872686/
https://ncbi.nlm.nih.gov/pubmed/20407012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-09-0493
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