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Structure-Dependent Inhibition of Bladder and Pancreatic Cancer Cell Growth by 2-Substituted Glycyrrhetinic and Ursolic Acid Derivatives

Derivatives of oleanolic acid, ursolic acid and glycyrrhetinic acid substituted with electron withdrawing groups at the 2-position in the A-ring which also contains a 1-en-3-one structure are potent inhibitors of cancer cell growth. In this study, we have compared the effects of several 2-substitute...

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Detalhes bibliográficos
Main Authors: Chadalapaka, Gayathri, Jutooru, Indira, McAlees, Alan, Stefanac, Tom, Safe, Stephen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2408873/
https://ncbi.nlm.nih.gov/pubmed/18359628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2008.03.031
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