Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis

Chemotactic cytokines (chemokines) can help regulate tumor cell invasion and metastasis. Here, we show that chemokine 25 (CCL25) and its cognate receptor chemokine receptor 9 (CCR9) inhibit colorectal cancer (CRC) invasion and metastasis. We found that CCR9 protein expression levels were highest in...

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Main Authors: Chen, Huanhuan Joyce, Edwards, Robert, Tucci, Serena, Bu, Pengcheng, Milsom, Jeff, Lee, Sang, Edelmann, Winfried, Gümüs, Zeynep H., Shen, Xiling, Lipkin, Steven
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Clinical Investigation 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428084/
https://ncbi.nlm.nih.gov/pubmed/22863617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62110
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