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Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis

Chemotactic cytokines (chemokines) can help regulate tumor cell invasion and metastasis. Here, we show that chemokine 25 (CCL25) and its cognate receptor chemokine receptor 9 (CCR9) inhibit colorectal cancer (CRC) invasion and metastasis. We found that CCR9 protein expression levels were highest in...

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Main Authors: Chen, Huanhuan Joyce, Edwards, Robert, Tucci, Serena, Bu, Pengcheng, Milsom, Jeff, Lee, Sang, Edelmann, Winfried, Gümüs, Zeynep H., Shen, Xiling, Lipkin, Steven
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2012
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428084/
https://ncbi.nlm.nih.gov/pubmed/22863617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62110
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