Chemokine 25–induced signaling suppresses colon cancer invasion and metastasis

Chemotactic cytokines (chemokines) can help regulate tumor cell invasion and metastasis. Here, we show that chemokine 25 (CCL25) and its cognate receptor chemokine receptor 9 (CCR9) inhibit colorectal cancer (CRC) invasion and metastasis. We found that CCR9 protein expression levels were highest in...

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Autori principali: Chen, Huanhuan Joyce, Edwards, Robert, Tucci, Serena, Bu, Pengcheng, Milsom, Jeff, Lee, Sang, Edelmann, Winfried, Gümüs, Zeynep H., Shen, Xiling, Lipkin, Steven
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Clinical Investigation 2012
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3428084/
https://ncbi.nlm.nih.gov/pubmed/22863617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI62110
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