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Prochelator BHAPI Protects Cells against Paraquat-Induced Damage by ROS-Triggered Iron Chelation

A prochelator named BHAPI (N′-(1-(2-(4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyloxy)phenyl)ethylidene)isonitotinohdrazide) based on the structure of experimental metal chelator HAPI (N′-[1-(2-hydroxyphenyl)ethyliden]isonicotinoylhydrazide) has been synthesized. The prochelator, which shows...

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Hlavní autoři: Kielar, Filip, Helsel, Marian E., Wang, Qin, Franz, Katherine J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427476/
https://ncbi.nlm.nih.gov/pubmed/22700084
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c2mt20069d
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