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A boronate prochelator built on a triazole framework for peroxide-triggered tridentate metal binding

Iron chelating agents have the potential to minimize damage associated with oxidative stress in a range of diseases; however, this potential is countered by risks of indiscriminant metal binding or iron depletion in conditions not associated with systemic iron overload. Deferasirox is a chelator use...

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Detalhes bibliográficos
Main Authors: Kielar, Filip, Wang, Qin, Boyle, Paul D., Franz, Katherine J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3579658/
https://ncbi.nlm.nih.gov/pubmed/23439614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ica.2012.06.011
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