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ROS-Triggered Degradable Iron-Chelating Nanogels: Safely Improving Iron Elimination in Vivo
Iron-mediated generation of highly toxic Reactive Oxygen Species (ROS) plays a major role in the process leading to iron overload-related diseases. The long-term subcutaneous administration of Deferoxamine (DFO) is currently clinically-approved to improve patient symptoms and survival. However, non-...
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| Publicado no: | J Control Release |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6035766/ https://ncbi.nlm.nih.gov/pubmed/29792889 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2018.05.025 |
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