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Enzymatically Biodegradable Polyrotaxane-Deferoxamine Conjugates for Iron Chelation

Chelation therapy is frequently used to help reduce excess iron in the body, but current chelators such as Deferoxamine (DFO) are plagued by short blood circulation times, which necessitates infusions and can cause undesirable toxic side effects in patients. To address these issues, polyrotaxanes (P...

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Bibliografski detalji
Izdano u:ACS Appl Mater Interfaces
Glavni autori: Liu, Zhi, Lin, Tien-min, Purro, Max, Xiong, May P.
Format: Artigo
Jezik:Inglês
Izdano: 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560162/
https://ncbi.nlm.nih.gov/pubmed/27623539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsami.6b09077
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