Loading...
MHC restriction is imposed on a diverse TCR repertoire by CD4 and CD8 coreceptors during thymic selection
Mature αβT cells recognize foreign antigenic peptides presented by MHC molecules but do not recognize native antigenic proteins , features known as MHC-restriction. How MHC-restriction is imposed on αβT cells has intrigued immunologists for decades. One model proposes that germline-encoded elements...
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2012
|
| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427466/ https://ncbi.nlm.nih.gov/pubmed/22771139 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.it.2012.05.006 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|