Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models

The accumulation of glomerular extracellular matrix (ECM) is one of the critical pathological characteristics of diabetic renal fibrosis. Fibronectin (FN) is an important constituent of ECM. Our previous studies indicate that the activation of the sphingosine kinase 1 (SphK1)-sphingosine 1- phosphat...

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Autors principals: Huang, Kaipeng, Liu, Weihua, Lan, Tian, Xie, Xi, Peng, Jing, Huang, Juan, Wang, Shaogui, Shen, Xiaoyan, Liu, Peiqing, Huang, Heqing
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427312/
https://ncbi.nlm.nih.gov/pubmed/22937115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043874
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