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Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models

The accumulation of glomerular extracellular matrix (ECM) is one of the critical pathological characteristics of diabetic renal fibrosis. Fibronectin (FN) is an important constituent of ECM. Our previous studies indicate that the activation of the sphingosine kinase 1 (SphK1)-sphingosine 1- phosphat...

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書誌詳細
主要な著者: Huang, Kaipeng, Liu, Weihua, Lan, Tian, Xie, Xi, Peng, Jing, Huang, Juan, Wang, Shaogui, Shen, Xiaoyan, Liu, Peiqing, Huang, Heqing
フォーマット: Artigo
言語:Inglês
出版事項: Public Library of Science 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427312/
https://ncbi.nlm.nih.gov/pubmed/22937115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043874
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