Berberine Reduces Fibronectin Expression by Suppressing the S1P-S1P2 Receptor Pathway in Experimental Diabetic Nephropathy Models

The accumulation of glomerular extracellular matrix (ECM) is one of the critical pathological characteristics of diabetic renal fibrosis. Fibronectin (FN) is an important constituent of ECM. Our previous studies indicate that the activation of the sphingosine kinase 1 (SphK1)-sphingosine 1- phosphat...

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Detalhes bibliográficos
Main Authors: Huang, Kaipeng, Liu, Weihua, Lan, Tian, Xie, Xi, Peng, Jing, Huang, Juan, Wang, Shaogui, Shen, Xiaoyan, Liu, Peiqing, Huang, Heqing
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3427312/
https://ncbi.nlm.nih.gov/pubmed/22937115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043874
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