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Reprogramming IgH isotype-switched B cells to functional-grade induced pluripotent stem cells
Induced pluripotent stem cells (iPSCs) can be formed from somatic cells by a defined set of genetic factors; however, aberrant epigenetic silencing of the imprinted Dlk1-Dio3 gene cluster often hinders their developmental potency and ability to contribute to high-grade chimerism in mice. Here, we de...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3427115/ https://ncbi.nlm.nih.gov/pubmed/22869756 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210286109 |
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