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Physiological role of the 3′IgH CBEs super-anchor in antibody class switching
IgH class switch recombination (CSR) replaces Cμ constant region (C(H)) exons with one of six downstream C(H)s by joining transcription-targeted double-strand breaks (DSBs) in the Cμ switch (S) region to DSBs in a downstream S region. Chromatin loop extrusion underlies fundamental CSR mechanisms inc...
Gorde:
| Argitaratua izan da: | Proc Natl Acad Sci U S A |
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| Egile Nagusiak: | , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
National Academy of Sciences
2021
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| Gaiak: | |
| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7826415/ https://ncbi.nlm.nih.gov/pubmed/33441485 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.2024392118 |
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