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Identification of hemopexin as an anti-inflammatory factor that inhibits synergy of hemoglobin with HMGB1 in sterile and infectious inflammation

Hemoglobin is released from lysed red blood cells in numerous clinical settings. HMGB1 is a nuclear and cytosolic DNA-binding protein released from injured cells that has been shown to play an important role in inducing inflammation. Because both of these endogenous molecules are frequently present...

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Autori principali: Lin, Tian, Sammy, Fatima, Yang, Huan, Thundivalappil, Sujatha, Hellman, Judith, Tracey, Kevin J., Warren, H. Shaw
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426910/
https://ncbi.nlm.nih.gov/pubmed/22772444
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103623
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