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Targeting HMGB1 in inflammation

High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein present in the nuclei and cytoplasm of nearly all cell types, is a necessary and sufficient mediator of inflammation during sterile and infection-associated responses. Elevated levels of HMGB1 in serum and tissues occur during...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Yang, Huan, Tracey, Kevin J.
Format: Artigo
Sprog:Inglês
Udgivet: 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4533842/
https://ncbi.nlm.nih.gov/pubmed/19948257
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbagrm.2009.11.019
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