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HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

A key question in immunology concerns how sterile injury activates innate immunity to mediate damaging inflammation in the absence of foreign invaders. The discovery that HMGB1, a ubiquitous nuclear protein, mediates the activation of innate immune responses led directly to the understanding that HM...

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Bibliografiska uppgifter
I publikationen:Annu Rev Immunol
Huvudupphovsmän: Andersson, Ulf, Tracey, Kevin J.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536551/
https://ncbi.nlm.nih.gov/pubmed/21219181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-030409-101323
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