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HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection

A key question in immunology concerns how sterile injury activates innate immunity to mediate damaging inflammation in the absence of foreign invaders. The discovery that HMGB1, a ubiquitous nuclear protein, mediates the activation of innate immune responses led directly to the understanding that HM...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Annu Rev Immunol
Prif Awduron: Andersson, Ulf, Tracey, Kevin J.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536551/
https://ncbi.nlm.nih.gov/pubmed/21219181
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-030409-101323
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