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HMGB1 Is a Therapeutic Target for Sterile Inflammation and Infection
A key question in immunology concerns how sterile injury activates innate immunity to mediate damaging inflammation in the absence of foreign invaders. The discovery that HMGB1, a ubiquitous nuclear protein, mediates the activation of innate immune responses led directly to the understanding that HM...
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| Publicado no: | Annu Rev Immunol |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536551/ https://ncbi.nlm.nih.gov/pubmed/21219181 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1146/annurev-immunol-030409-101323 |
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