Hemopexin in severe inflammation and infection: mouse models and human diseases

INTRODUCTION: Cell-free plasma hemoglobin is associated with poor outcome in patients with sepsis. Extracellular hemoglobin and secondarily released heme amplify inflammation in the presence of microbial TLR ligands and/or endogenous mediators. Hemopexin, a plasma protein that binds heme with extrao...

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Veröffentlicht in:Crit Care
Hauptverfasser: Lin, Tian, Maita, Dayana, Thundivalappil, Sujatha R, Riley, Frank E, Hambsch, Jasmin, Van Marter, Linda J, Christou, Helen A, Berra, Lorenzo, Fagan, Shawn, Christiani, David C, Warren, H Shaw
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4424824/
https://ncbi.nlm.nih.gov/pubmed/25888135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13054-015-0885-x
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