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Hepatic Immunosuppressive Effects of Systemically-Administered Novel Dextran-Methylprednisolone Prodrugs with Peptide Linkers in Rats

The hepatic immunosuppressive activities of two novel dextran prodrugs of methylprednisolone (MP) containing one (DMP1) or five (DMP5) amino acids as linkers were studied in rats. At various times (0–2 weeks) after intravenous administration of single 5-mg/kg (MP equivalent) doses of each prodrug or...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Shaik, Imam H., Agarwal, Hitesh K., Parang, Keykavous, Mehvar, Reza
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426655/
https://ncbi.nlm.nih.gov/pubmed/22829462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jps.23274
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