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Effects of Methylprednisolone and Its Liver-Targeted Dextran Prodrug on Ischemia-Reperfusion Injury in a Rat Liver Transplantation Model

PURPOSE: To evaluate the effectiveness of a liver-targeted dextran prodrug (DMP) of methylprednisolone (MP) in cold preservation-warm reperfusion injury associated with liver transplantation. METHODS: The effects of donor pretreatment with single 5-mg/kg doses of MP or DMP on ischemia-reperfusion da...

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Main Authors: Chimalakonda, Anjaneya P., Mehvar, Reza
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2094048/
https://ncbi.nlm.nih.gov/pubmed/17922174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-007-9414-1
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