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Quantitative Analysis of α-Synuclein Solubility in Living Cells Using Split GFP Complementation

Presently incurable, Parkinson's disease (PD) is the most common neurodegenerative movement disorder and affects 1% of the population over 60 years of age. The hallmarks of PD pathogenesis are the loss of dopaminergic neurons in the substantia nigra pars compacta, and the occurrence of proteina...

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Bibliografiske detaljer
Main Authors: Kothawala, Ahmed, Kilpatrick, Kiri, Novoa, Jose Andres, Segatori, Laura
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425482/
https://ncbi.nlm.nih.gov/pubmed/22927976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0043505
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