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Hsc70 Protein Interaction with Soluble and Fibrillar α-Synuclein
The aggregation of α-synuclein (α-Syn), the primary component of Lewy bodies, into high molecular weight assemblies is strongly associated with Parkinson disease. This event is believed to result from a conformational change within native α-Syn. Molecular chaperones exert critical housekeeping funct...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3186418/ https://ncbi.nlm.nih.gov/pubmed/21832061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.261321 |
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