Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice

We recently demonstrated that reducing IGF-1 receptor (IGF-1R) numbers in the endothelium enhances nitric oxide (NO) bioavailability and endothelial cell insulin sensitivity. In the present report, we aimed to examine the effect of increasing IGF-1R on endothelial cell function and repair. To examin...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Imrie, Helen, Viswambharan, Hema, Sukumar, Piruthivi, Abbas, Afroze, Cubbon, Richard M., Yuldasheva, Nadira, Gage, Matthew, Smith, Jessica, Galloway, Stacey, Skromna, Anna, Rashid, Sheik Taqweer, Futers, T. Simon, Xuan, Shouhong, Gatenby, V. Kate, Grant, Peter J., Channon, Keith M., Beech, David J., Wheatcroft, Stephen B., Kearney, Mark T.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Diabetes Association 2012
Gaiak:
Pathophysiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425420/
https://ncbi.nlm.nih.gov/pubmed/22733797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1494
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