Novel Role of the IGF-1 Receptor in Endothelial Function and Repair: Studies in Endothelium-Targeted IGF-1 Receptor Transgenic Mice

We recently demonstrated that reducing IGF-1 receptor (IGF-1R) numbers in the endothelium enhances nitric oxide (NO) bioavailability and endothelial cell insulin sensitivity. In the present report, we aimed to examine the effect of increasing IGF-1R on endothelial cell function and repair. To examin...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Imrie, Helen, Viswambharan, Hema, Sukumar, Piruthivi, Abbas, Afroze, Cubbon, Richard M., Yuldasheva, Nadira, Gage, Matthew, Smith, Jessica, Galloway, Stacey, Skromna, Anna, Rashid, Sheik Taqweer, Futers, T. Simon, Xuan, Shouhong, Gatenby, V. Kate, Grant, Peter J., Channon, Keith M., Beech, David J., Wheatcroft, Stephen B., Kearney, Mark T.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Diabetes Association 2012
Onderwerpen:
Pathophysiology
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3425420/
https://ncbi.nlm.nih.gov/pubmed/22733797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1494
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items