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Active site opening and closure control translocation of multisubunit RNA polymerase
Multisubunit RNA polymerase (RNAP) is the central information-processing enzyme in all cellular life forms, yet its mechanism of translocation along the DNA molecule remains conjectural. Here, we report direct monitoring of bacterial RNAP translocation following the addition of a single nucleotide....
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Oxford University Press
2012
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424550/ https://ncbi.nlm.nih.gov/pubmed/22570421 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks383 |
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