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Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion
Exposure to reactive oxygen species (ROS) can give rise to the formation of various DNA damage products. Among them, d(G[8-5 m]T) can be induced in isolated DNA treated with Fenton reagents and in cultured human cells exposed to γ-rays, d(G[8-5m]T) can be recognized and incised by purified Escherich...
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| 主要な著者: | , , , , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
2012
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3424544/ https://ncbi.nlm.nih.gov/pubmed/22581771 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks357 |
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