Endogenous formation and repair of oxidatively induced G[8-5 m]T intrastrand cross-link lesion

Exposure to reactive oxygen species (ROS) can give rise to the formation of various DNA damage products. Among them, d(G[8-5 m]T) can be induced in isolated DNA treated with Fenton reagents and in cultured human cells exposed to γ-rays, d(G[8-5m]T) can be recognized and incised by purified Escherich...

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Detalhes bibliográficos
Main Authors: Wang, Jin, Cao, Huachuan, You, Changjun, Yuan, Bifeng, Bahde, Ralf, Gupta, Sanjeev, Nishigori, Chikako, Niedernhofer, Laura J., Brooks, Philip J., Wang, Yinsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2012
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424544/
https://ncbi.nlm.nih.gov/pubmed/22581771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks357
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