Intravenous Administration of Adenoviruses Targeting Transforming Growth Factor Beta Signaling Inhibits Established Bone Metastases in 4T1 Mouse Mammary Tumor Model in an Immunocompetent Syngeneic Host

We have examined the effect of adenoviruses expressing soluble transforming growth factor receptorII-Fc (sTGFβRIIFc) in a 4T1 mouse mammary tumor bone metastasis model using syngeneic BALB/c mice. Infection of 4T1 cells with a non-replicating adenovirus, Ad(E1-).sTβRFc, or with two oncolytic adenovi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Zhang, Zhenwei, Hu, Zebin, Gupta, Janhavi, Krimmel, Jeffrey, Gerseny, Helen, Berg, Arthur, Robbins, John, Du, Hongyan, Prabhakar, Bellur, Seth, Prem
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424293/
https://ncbi.nlm.nih.gov/pubmed/22744210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cgt.2012.41
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados